Publications in 2011

Journal Articles (subsidised)

AERTS R, THIJS KW, LEHOUCK V, BEENTJE H, BYTEBIER BLG, MATTHYSEN E, GULINCK H, LENS L, MUYS B. Woody plant communities of isolated Afromontane cloud forests in Taita Hills, Kenya. Plant Ecology 2011; 212 : 639-649.

AFRICANDER D, LOUW R, VERHOOG N, NOETH D, HAPGOOD JP. Differential regulation of endogenous pro-inflammatory cytokine genes by medroxyprogesterone acetate and norethisterone acetate in cell lines of the female genital tract. Contraception 2011; 84(4) : 423-435.

AFRICANDER D, VERHOOG N, HAPGOOD JP. Molecular mechanisms of steroid receptor-mediated actions by synthetic progestins used in HRT and contraception. Steroids 2011; 76 : 636-652.

BYTEBIER BLG, ANTONELLI A, BELLSTEDT DU, LINDER HP. Estimating the age of fire in the Cape flora of South Africa from an orchid phylogeny. Proceedings of the Royal Society B-Biological Sciences 2011; 278 : 188-195.

CLOETE WJ, ADRIAANSE C, SWART P, KLUMPERMAN B. Facile immobilization of enzymes on electrospun poly(styrene-alt-maleic anhydride) nanofibres. Polymer Chemistry 2011; 2 : 1479-1481.

COUVREUR TLP, PIRIE MD, CHATROU LW, SAUNDERS RMK, SU YCF, RICHARDSON JE, ERKENS RHJ. Early evolutionary history of the flowering plant family Annonaceae: steady diversification the boreotropical geodispersal. Journal of Biogeography 2011; 38 : 664-680.

DAVIES TJ, SMITH GF, BELLSTEDT DU, BOATWRIGHT JS, BYTEBIER BLG, COWLING RM, FOREST F, HARMON LJ, MUASYA AM, SCHRIRE B, STEENKAMP Y, VAN DER BANK M, SAVOLAINEN V. Extinction Risk and Diversification Are Linked in a Plant Biodiversity Hotspot. Plos Biology 2011; 9(5) : e1000620.

DEKKER S, CILLIERS P, HOFMEYR J-HS. The complexity of failure: Implications of complexity theory for safety investigations. Safety Science 2011; 49 : 939-945.

GOOSEN P, STORBECK K-H, SWART AC, CONRADIE R, SWART P. Cytochrome b5 augments 3ß-hydroxysteroid dehydrogenase/∆5-∆4 isomerase activity. Journal of Steroid Biochemistry and Molecular Biology 2011; 127 : 238-247.

HADLEY K, LOUW A, HAPGOOD JP. Differential nuclear localisation and promoter occupancy play a role in glucocorticoid receptor ligand-specific transcriptional responses. Steroids 2011; 76 : 1176-1184.

HOFMEYR J-HS, ROHWER JM. Supply-Demand Analysis: A Framework for Exploring the Regulatory Design of Metabolism. Methods in Enzymology 2011; 500(Chapter 25) : 533-554.

LARSSON C, SNOEP JL, NORBECK J, ALBERS E. Flux balance analysis for ethylene formation in genetically engineered Saccharomyces cerevisiaeIET Systems Biology 2011; 5(4) : 245-251.

MFA MEZUI A, SWART P. Effect of UV-C Disinfection of Beer – Sensory Analysis and Consumer Ranking. Journal of the Institute of Brewing 2010; 116(4) : 348-353.

OBERLANDER KC, DREYER LL, BELLSTEDT DU. Molecular phylogenetics and origins of southern African OxalisTaxon 2011; 60(6) : 1667-1677.

PILLAY CS, HOFMEYR J-HS, ROHWER JM. The logic of kinetic regulation in the thioredoxin system. BMC SYSTEMS BIOLOGY 2011; 5 : 15.

PIRIE MD, OLIVER EGH, BELLSTEDT DU. A densely sampled ITS phylogeny of the Cape flagship genus Erica L. suggests numerous shifts in floral macro-morphology . Molecular Phylogenetics and Evolution 2011; 61 : 593–601.

SHERIDAN CM, GLASSER D, HILDEBRANDT D, PETERSEN J, ROHWER JM. An Annual and Seasonal

Characterisation of Winery Effluent in South Africa. South African Journal of Enology and Viticulture 2011; 32(1) : 1-8.

SISSING L, MARNEWICK JL, DE KOCK M, SWANEVELDER S, JOUBERT E, GELDERBLOM WCA. Modulating effects of rooibos and honeybush herbal teas on the development of esophageal papillomas in rats. Nutrition and Cancer-An International Journal 2011; 63(4) : 600-610.

VAN DER WESTHUIZEN L, SHEPHARD GS, BURGER H.-M., RHEEDER JP, GELDERBLOM WCA, WILD CP, GONG YY. Fumonisin B1 as a Urinary Biomarker of Exposure in a Maize Invervention Study Among South African Subsistence Farmers. Cancer Epidemiology Biomarkers & Prevention 2011; 20 : 483-489.

VAN DER WESTHUIZEN L, SHEPHARD GS, RHEEDER JP, BURGER H.-M., GELDERBLOM WCA, WILD CP, GONG YY. Optimising sorting and washing of home-grown maize to reduce fumonisin contamination under laboratory-controlled conditions. Food Control 2011; 22 : 396-400.

WALTEMATH D, ADAMS R, BEARD DA, BERGMAN FT, BHALLA U S, BRITTEN R, CHELLIAH V, COOLING MT, COOPER J, CRAMPIN E J , GARNY A, HOOPS S, HUCKA M, HUNTER P, KLIPP E, LAIBE C, MILLER AK, MORARU I, NICKERSON D, NIELSEN P, NIKOLSKI M, SAHLE S, SAURO H, SCHMIDT H,. Minimum Information About a Simulation Experiment (MIASE). Plos Computational Biology 2011; 7(4) : e1001122.

WALTEMATH D, ADAMS R, BERGMANN FT, HUCKA M, KOLPAKOV F, MILLER AK, MORARU I, NICKERSON D, SAHLE S, SNOEP JL, LE NOVÈRE N . Reproducible computational biology experiments with SED-ML – The Simulation Experiment Description Markup Language. BMC SYSTEMS BIOLOGY 2011; 5(198) : 175-0505: 1-10.

WARREN BH, BAKKER FT, BELLSTEDT DU, BYTEBIER BLG, CLABEN-BOCKHOFF R, DREYER LL, EDWARDS D, FOREST F, GALLEY C, HARDY CR, LINDER HP, MUASYA AM, MUMMENHOFF K, OBERLANDER KC, QUINT M, RICHARDSON JE, SAVOLAINEN V, VAN DER NIET T , SCHRIRE B, VAN DER NIET T , . Consistent phenological shifts in the making of a biodiversity hotspot: the Cape flora. BMC Evolutionary Biology 2011; 11(39) : 1-11.

WOLSTENCROFT K, OWEN S, DU PREEZ F, KREBS O, MUELLER W, GOBLE C, SNOEP JL. The Seek: A Platform for Sharing Data and Models in Systems Biology. Methods in Enzymology 2011; 500(Chapter 29) : 629-655.

WOLSTENCROFT K, OWEN S, HORRIDGE M, KREBS O, MUELLER W, SNOEP JL, DU PREEZ F, GOBLE C. RightField: embedding ontology annotation in spreadsheets. Bioinformatics 2011; 27(14) : 2021-2022.

Journal Articles (NON-subsidised)

SWAT M, KIELBASA SM, POLAK S, OLIVIER BG, BRUGGEMAN F, TULLOCH MQ, SNOEP JL, VERHOEVEN AJ, WESTERHOFF HW. What it takes to understand and cure a living system: computational systems biology and a systems biology-driven pharmacokinetics-pharmacodynamics platform. Interface Focus 2011; 1 : 16-23.

Chapters in Books

HUGENHOLTZ J, HOLS P, SNOEP JL. Metabolic engineering of lactic acid bacteria. In Thirty years of research on lactic acid bacteria. (ISBN 978-90-817671-0-1), 24 Media Labs, Rotterdam, Netherlands, 2011: 113-133.

Doctoral completed

AKHURST TJSymbolic control analysis of cellular systems. PhD(Bioch), 2011. 193 pp. Promotor: Rohwer JM. Medepromotor: Hofmeyr J-HS.

EYÉGHÉ-BIKONG HARole of surfactin from Bacillus subtilis in protection against antimicrobial peptides produced by Bacillus species. PhD(Bioch), 2011. 239 pp. Promotor: Rautenbach M.

ROBERTSON SReceptor concentration affects glucocorticoid action. PhD(Bioch), 2011. 200 pp. Promotor: Louw A. Medepromotor: Hapgood JP.

Masters completed

CROUS CSupply-demand analysis of anaerobic free-energy metabolism in Zymomonas mobilis. MSc Biochemie, 2011. 85 pp. Studieleier: Rohwer JM. Medestudieleier: Snoep JL.

DU PLESSIS DMFabrication and characterization of anti-microbial and biofouling resistant nanofibers with silver nanoparticles and immobilized enzymes for application in water filtration. MSc Biochemie, 2011. 94 pp. Studieleier: Cloete TE. Medestudieleier: Dicks LTM, Swart P.

GQWAKA OPCA generic rate equotion for catalysed, template-directed polymerisation and its use in computational systems biology. MSc Biochemie, 2011. 111 pp. Studieleier: Hofmeyr J-HS. Medestudieleier: Rohwer JM.

JANA CESynthesis and evaluation of pantothenic acid analogues as potential inhibitors of malaria parasites and bacteria. MSc Biochemie, 2011. 99 pp. Studieleier: Strauss E.

JORDAAN SSupply-demand analysis of energy metabolism in Lactococcus Lactis under anerobic conditions. MSc Biochemie, 2011. 83 pp. Studieleier: Rohwer JM. Medestudieleier: Snoep JL.