Bone Pathology Database

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2nd image
Xray of elbow
The x rays show a non specific lytic lesion of the distal tibia and of the olecranon in the adjacent image.
Biopsy plays an important role in the diagnosis and monitoring the response to chemotherapy of lymphomata. The biopsy confirmed a B cell lymphoma with much cell necrosis after the chemotherapy.

XRAY: Findings vary so much that none are considered characteristic. Extensive, involving 25-50% of affected bone, sometimes entire bone. Destructive lesion: radiolucent, mottled, patchy, motheaten and sometimes the outline of the bone is complete lost. Infiltrative , permeative, poorly defined interface with normal bone. 50% have a mixture with small areas of sclerosis. Nearly all destroy cortical bone and 25% thicken the cortex. Often large, obvious soft-tissue extension. Periosteal new bone formation uncommon. Sclerosis may preceed diagnosis by several years and in flat bones may resemble Paget's. When confined to marrow cavity, plain x-ray negative but bone scan and MRI positive. A classic presentation of (rear) Hodgkins disease in bone is the solitary ivory vertebra. 25% present with pathologic fracture.

Record 49