Patients and Methods
Tygerberg bone tumor records used and all cases of histologically proven giant cell tumor over the last 20 years were included. Follow up varied from 15 years to a few months (2 fatal terminations)
Lesions which mimicked Giant cell tumor were 2 cases of brown tumor (Hyperparathyriodism)
and Aneurismal bone cyst often resembled giant cell tumor and histology was
essential to make the discrimination. We routinely biopsy suspected tumors before
the definitive procedure is done.