Jannie Hofmeyr is co-founder of the CST and emeritus professor of biochemistry and biocomplexity at Stellenbosch University. Over the past 35 years, he has conducted his research in the field of Computational System Biology with the regulation and regulatory design of metabolism as his main focus. More recently, his work focuses on describing the functional organisation of the living cell for which he developed a theory of molecular fabrication to inform a theoretical basis for both system biology and nanotechnology. During 2017-18 he was the president of the Royal Society of South Africa (RSSAf).