Publications 2019

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Ali, D.; Hunter, R.; Kaschula, C. H.; De Doncker, S.; Rees-Jones, S. C. M. Unsymmetrical Organotrisulfide Formation via Low-Temperature Disulfanyl Anion Transfer to an Organothiosulfonate. J. Org. Chem. 2019, 84 (5), 2862–2869. https://doi.org/10.1021/acs.joc.8b03262.
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Barnard, I.; Koch, K. R. 59Co NMR, a Facile Tool to Demonstrate EEE, EEZ, EZZ and ZZZ Configurational Isomerism in Fac-[Co(L-ΚS,O)3] Complexes Derived from Asymmetrically Substituted N,N-Dialkyl-N’-Aroylthioureas. Inorg. Chim. Acta 2019, 495 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 119019. https://doi.org/10.1016/j.ica.2019.119019.
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Blanckenberg, A.; Malgas-Enus, Rehana. Raspberry-like Gold-Decorated Silica (SSx-AMPS-Au) Nanoparticles for the Reductive Discoloration of Dyes. SN Appl. Sci. 2019, 1 (7), 1–13. https://doi.org/10.1007/s42452-019-0821-9.
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Blanckenberg, A.; Malgas-Enus, Rehana. Olefin Epoxidation with Metal-Based Nanocatalysts. Catal. Rev.: Sci. Eng. 2019, 61 (1), 27–83. https://doi.org/10.1080/01614940.2018.1492503.
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Bleloch, J. S.; du Toit, A.; Gibhard, L.; Kimani, S.; Ballim, R. D.; Lee, M.; Blanckenberg, A.; Mapolie, S.; Wiesner, L.; Loos, B.; Prince, Sharon. The Palladacycle Complex AJ-5 Induces Apoptotic Cell Death While Reducing Autophagic Flux in Rhabdomyosarcoma Cells. Cell Death Discovery 2019, 5 (1), 1–16. https://doi.org/10.1038/s41420-019-0139-9.
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Chellan, P.; Stringer, T.; Shokar, A.; Au, A.; Tam, C.; Cheng, L. W.; Smith, G. S.; Land, K. M. Antiprotozoal Activity of Palladium(II) Salicylaldiminato Thiosemicarbazone Complexes on Metronidazole Resistant Trichomonas Vaginalis. Inorg. Chem. Commun. 2019, 102 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 1–4. https://doi.org/10.1016/j.inoche.2019.01.033.
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Cimmino, A.; Nimis, P. L.; Masi, M.; De Gara, L.; van Otterlo, W. A. L.; Kiss, R.; Evidente, A.; Lefranc, Florence. Have Lichenized Fungi Delivered Promising Anticancer Small Molecules. Phytochem. Rev. 2019, 18 (1), 1–36. https://doi.org/10.1007/s11101-018-9577-x.
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Claassens, I. E.; Barbour, L. J.; Haynes, D. A. A Multistimulus Responsive Porous Coordination Polymer: Temperature-Mediated Control of Solid-State [2+2] Cycloaddition. J. Am. Chem. Soc. 2019, 141 (29), 11425–11429. https://doi.org/10.1021/jacs.9b05961.
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Clements, M.; Blackie, M.; de Kock, C.; Lawrence, N.; Smith, P.; Le Roex, Tanya. Investigation into the Structures and Properties of Multicomponent Crystals Formed from a Series of 7-Chloroquinolines and Aromatic Acids. Cryst. Growth Des. 2019, 19 (3), 1540–1549. https://doi.org/10.1021/acs.cgd.8b01049.
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Cloete, W. J.; Hayward, S.; Swart, P.; Klumperman, Bert. Degradation of Proteins and Starch by Combined Immobilization of Protease, α-Amylase and β-Galactosidase on a Single Electrospun Nanofibrous Membrane. Molecules 2019, 24 (3), 508/1-508/9. https://doi.org/10.3390/molecules24030508.
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Dasari, R.; Blauz, A.; Medellin, D. C.; Kassim, R. M.; Viera, C.; Santarosa, M.; van der Westhuyzen, A. E.; van Otterlo, W. A. L.; Olivas, T.; Yildiz, T.; Betancourt, T.; Shuster, C. B.; Rogelj, S.; Rychlik, B.; Hudnall, T.; Frolova, L. V.; Kornienko, Alexander. Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins: Exploration of the N3 and N9 Positions and Interaction with Multidrug-Resistance Proteins. ChemMedChem 2019, 14 (3), 322–333. https://doi.org/10.1002/cmdc.201800658.
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de Kock, S.; Dillen, J.; Esterhuysen, Catharine. Steric and Electronic Effects in Gold N-Heterocyclic Carbene Complexes Revealed by Computational Analysis. ChemistryOpen 2019, No. Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved., Ahead of Print. https://doi.org/10.1002/open.201900076.
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Dembaremba, T. O.; Correia, I.; Hosten, E. C.; Kuznetsov, M. L.; Gerber, W. J.; Pessoa, J. C.; Ogunlaja, A. S.; Tshentu, Z. R. New VIVO-Complexes for Oxidative Desulfurization of Refractory Sulfur Compounds in Fuel: Synthesis, Structure, Reactivity Trend and Mechanistic Studies. Dalton Trans. 2019, 48 (44), 16687–16704. https://doi.org/10.1039/c9dt02505g.
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Domingo, R.; van der Westhuyzen, R.; Hamann, A. R.; Mostert, K. J.; Barnard, L.; Paquet, T.; Tjhin, E. T.; Saliba, K. J.; van Otterlo, W. A. L.; Strauss, Erick. Overcoming Synthetic Challenges in Targeting Coenzyme A Biosynthesis with the Antimicrobial Natural Product CJ-15,801. MedChemComm 2019, 10 (12), 2118–2125. https://doi.org/10.1039/c9md00312f.
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Eselem Bungu, P. S.; Pasch, Harald. Bivariate Molecular Structure Distribution of Randomly Branched Polyethylene by Orthogonal Preparative Fractionation. Polym. Chem. 2019, 10 (19), 2484–2494. https://doi.org/10.1039/c9py00343f.
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Groenewald, F.; Raubenheimer, H. G.; Dillen, J.; Esterhuysen, Catharine. Computational Investigation of Au·H Hydrogen Bonds Involving Neutral AuIN-Heterocyclic Carbene Complexes and Amphiprotic Binary Hydrides. J. Mol. Model. 2019, 25 (5), 1–16. https://doi.org/10.1007/s00894-019-4018-3.
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Groenewald, F.; Raubenheimer, H. G.; Dillen, J.; Esterhuysen, C. Computational Investigation of Au·H Hydrogen Bonds Involving Neutral Au(I) N-Heterocyclic Carbene Complexes and Amphiprotic Binary Hydrides. J Mol Model 2019, 25 (5), 135.
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Hazra, A.; van Heerden, D. P.; Sanyal, S.; Lama, P.; Esterhuysen, C.; Barbour, L. J. CO2-Induced Single-Crystal to Single-Crystal Transformations of an Interpenetrated Flexible MOF Explained by in Situ Crystallographic Analysis and Molecular Modeling. Chem. Sci. 2019, 10 (43), 10018–10024. https://doi.org/10.1039/c9sc04043a.
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Heyns, I. M.; Pfukwa, R.; Bertossi, L.; Ball, L. E.; Kelland, M. A.; Klumperman, Bert. Thermoresponsive Behavior of Poly(3-Methylene-2-Pyrrolidone) Derivatives. Eur. Polym. J. 2019, 112 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 714–721. https://doi.org/10.1016/j.eurpolymj.2018.10.040.
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Johnson, M. M.; Naidoo, J. M.; Fernandes, M. A.; Mmutlane, E. M.; van Otterlo, W. A. L.; de Koning, C. B. Correction to CAN-Mediated Oxidations for the Synthesis of Xanthones and Related Products. J. Org. Chem. 2019, 84 (1), 472. https://doi.org/10.1021/acs.joc.8b02352.
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Jurisch, C. D.; Arnott, G. E. Attempted Synthesis of a Meta-Metalated Calix[4]Arene. Beilstein J. Org. Chem. 2019, 15 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 1996–2002. https://doi.org/10.3762/bjoc.15.195.
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Kargaard, A.; Sluijter, J. P. G.; Klumperman, Bert. Polymeric SiRNA Gene Delivery - Transfection Efficiency versus Cytotoxicity. J. Controlled Release 2019, 316 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 263–291. https://doi.org/10.1016/j.jconrel.2019.10.046.
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Kaschula, C. H.; Tuveri, R.; Ngarande, E.; Dzobo, K.; Graham, L. M.; Katz, A. A.; Parker, M. I.; Schafer, G.; Dzobo, K.; Barnett, C.; Kusza, D. A.; Hunter, R.; Rafudeen, M. S. The Garlic Compound Ajoene Covalently Binds Vimentin, Disrupts the Vimentin Network and Exerts Anti-Metastatic Activity in Cancer Cells. BMC Cancer 2019, 19 (1), 248.
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Lama, P.; Hazra, A.; Barbour, L. J. Accordion and Layer-Sliding Motion to Produce Anomalous Thermal Expansion Behaviour in 2D-Coordination Polymers. Chem. Commun. (Cambridge, U. K.) 2019, 55 (80), 12048–12051. https://doi.org/10.1039/c9cc06634a.
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Lategahn, J.; Keul, M.; Kloevekorn, P.; Tumbrink, H. L.; Niggenaber, J.; Mueller, M. P.; Hodson, L.; Flasshoff, M.; Hardick, J.; Grabe, T.; Engel, J.; Schultz-Fademrecht, C.; Baumann, M.; Ketzer, J.; Muehlenberg, T.; Hiller, W.; Guenther, G.; Unger, A.; Mueller, H.; Heimsoeth, A.; Golz, C.; Blank-Landeshammer, B.; Kollipara, L.; Zahedi, R. P.; Strohmann, C.; Hengstler, J. G.; van Otterlo, W. A. L.; Bauer, S.; Rauh, Daniel. Inhibition of Osimertinib-Resistant Epidermal Growth Factor Receptor EGFR-T790M/C797S. Chem. Sci. 2019, 10 (46), 10789–10801. https://doi.org/10.1039/c9sc03445e.
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Leckie, L.; Mapolie, S. F. Triazole Complexes of Ruthenium Immobilized on Mesoporous Silica as Recyclable Catalysts for Octane Oxidation. Catal. Commun. 2019, 131 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 105803pp. https://doi.org/10.1016/j.catcom.2019.105803.
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Mabank, T.; Alexandre, K. B.; Pelly, S. C.; Green, I. R.; van Otterlo, W. A. L. Synthesis of 2-Substituted Tetrahydroisoquinolin-6-Ols: Potential Scaffolds for Estrogen Receptor Modulation and/or Microtubule Degradation. ARKIVOC (Gainesville, FL, U. S.) 2019, No. 4, 245–279. https://doi.org/10.24820/ark.5550190.p010.962.
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Masi, M.; Van slambrouck, S.; Gunawardana, S.; van Rensburg, M. J.; James, P. C.; Mochel, J. G.; Heliso, P. S.; Albalawi, A. S.; Cimmino, A.; van Otterlo, W. A. L.; Kornienko, A.; Green, I. R.; Evidente, A. Alkaloids Isolated from Haemanthus Humilis Jacq., an Indigenous South African Amaryllidaceae: Anticancer Activity of Coccinine and Montanine. S. Afr. J. Bot. 2019, 126 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 277–281. https://doi.org/10.1016/j.sajb.2019.01.036.
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Mosekiemang, T. T.; Stander, M. A.; de Villiers, Andre. Simultaneous Quantification of Commonly Prescribed Antiretroviral Drugs and Their Selected Metabolites in Aqueous Environmental Samples by Direct Injection and Solid Phase Extraction Liquid Chromatography - Tandem Mass Spectrometry. Chemosphere 2019, 220 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 983–992. https://doi.org/10.1016/j.chemosphere.2018.12.205.
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Muller, M.; Tredoux, A. G. J.; de Villiers, Andre. Application of Kinetically Optimised Online HILIC × RP-LC Methods Hyphenated to High Resolution MS for the Analysis of Natural Phenolics. Chromatographia 2019, 82 (1), 181–196. https://doi.org/10.1007/s10337-018-3662-6.
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Murima, D.; Pasch, Harald. Comprehensive Branching Analysis of Star-Shaped Polystyrenes Using a Liquid Chromatography-Based Approach. Anal. Bioanal. Chem. 2019, 411 (20), 5063–5078. https://doi.org/10.1007/s00216-019-01846-7.
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Muza, U. L.; Pasch, Harald. Thermal Field-Flow Fractionation with Quintuple Detection for the Comprehensive Analysis of Complex Polymers. Anal. Chem. (Washington, DC, U. S.) 2019, 91 (10), 6926–6933. https://doi.org/10.1021/acs.analchem.9b01384.
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Ndiripo, A.; Pornwilard, M.-M.; Pathaweeisariyakul, T.; Pasch, Harald. Multidimensional Chromatographic Analysis of Carboxylic Acid-Functionalized Polyethylene. Polym. Chem. 2019, 10 (43), 5859–5869. https://doi.org/10.1039/c9py01191a.
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Ndiripo, A.; Eselem Bungu, P. S.; Pasch, Harald. Comprehensive Branching Analysis of Polyethylene by Combined Fractionation and Thermal Analysis. Polym. Int. 2019, 68 (2), 206–217. https://doi.org/10.1002/pi.5547.
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Nkabyo, H. A.; Koch, K. R. Configurational E/Z and Photo-Induced Cis-Trans Isomerism in the Pd(II) Complex of Asymmetrical N,N-Methyl-Ethyl-N’-Benzoylthiourea. J. Mol. Struct. 2019, 1190 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 47–53. https://doi.org/10.1016/j.molstruc.2019.04.038.
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Nkabyo, H. A.; Procacci, B.; Duckett, S. B.; Koch, K. R. Reversible Photo-Isomerization of Cis-[Pd(L-ΚS,O)2] (HL = N,N-Diethyl-N’-1-Naphthoylthiourea) to Trans-[Pd(L-ΚS,O)2] and the Unprecedented Formation of Trans-[Pd(L-ΚS,N)2] in Solution. Dalton Trans. 2019, 48 (46), 17241–17251. https://doi.org/10.1039/c9dt03672e.
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Ogutu, H. F. O.; Saban, W.; Malgas-Enus, R.; Luckay, R. C. Synthesis and Characterization of 5- and 7-Donor Schiff Base Ligands and Spectroscopic Evidence for Tautomerism: A Crystal Structure Showing Tautomeric Forms within One Ligand. J. Mol. Struct. 2019, 1185 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 392–402. https://doi.org/10.1016/j.molstruc.2019.02.054.
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Overduin, M.; Klumperman, Bert. Advancing Membrane Biology with Poly(Styrene-Co-Maleic Acid)-Based Native Nanodiscs. Eur. Polym. J. 2019, 110 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 63–68. https://doi.org/10.1016/j.eurpolymj.2018.11.015.
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Pearce, B. H.; Ogutu, H. F. O.; Saban, W.; Luckay, R. C. Synthesis, Characterization and Use of Imidazole and Methyl-Pyrazole Based Pyridine Ligands as Extractants for Nickel(II) and Copper(II). Inorg. Chim. Acta 2019, 490 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 57–67. https://doi.org/10.1016/j.ica.2019.02.020.
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Pribut, N.; Basson, A. E.; van Otterlo, W. A. L.; Liotta, D. C.; Pelly, S. C. Aryl Substituted Benzimidazolones as Potent HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors. ACS Med. Chem. Lett. 2019, 10 (2), 196–202. https://doi.org/10.1021/acsmedchemlett.8b00549.
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Radebe, N. W.; Beskers, T.; Greyling, G.; Pasch, H. Online Coupling of Thermal Field-Flow Fractionation and Fourier Transform Infrared Spectroscopy as a Powerful Tool for Polymer Characterization. J. Chromatogr. A 2019, 1587 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 180–188. https://doi.org/10.1016/j.chroma.2018.12.012.
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Rokohl, A. C.; Koch, K. R.; Heindl, L. M.; Kabbasch, C.; Kreppel, M.; Luers, J.-C.; Grau, S.; Grau, S.; Heindl, L. M. Importance of Interdisciplinary Collaboration for Optimal Treatment of Orbital Tumors. HNO 2019, 67 (7), 528–533.
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Sikiti, P.; Bezuidenhout, C. X.; van Heerden, D. P.; Barbour, L. J. Direct in Situ Crystallographic Visualization of a Dual Mechanism for the Uptake of CO2 Gas by a Flexible Metal-Organic Framework. Inorg. Chem. 2019, 58 (13), 8257–8262. https://doi.org/10.1021/acs.inorgchem.9b00761.
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Sikiti, P.; Bezuidenhout, C. X.; van Heerden, D. P.; Barbour, L. J. A New Dynamic Framework with Direct in Situ Visualisation of Breathing under CO2 Gas Pressure. CrystEngComm 2019, 21 (22), 3415–3419. https://doi.org/10.1039/c9ce00418a.
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Singh, A. P.; Singh, R.; Verma, S. S.; Rai, V.; Kaschula, C. H.; Maiti, P.; Gupta, S. Chandra. Health Benefits of Resveratrol: Evidence from Clinical Studies. Med. Res. Rev. 2019, 39 (5), 1851–1891. https://doi.org/10.1002/med.21565.
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van Niekerk, A.; Chellan, P.; Mapolie, S. F. Heterometallic Multinuclear Complexes as Anti-Cancer Agents-An Overview of Recent Developments. Eur. J. Inorg. Chem. 2019, 2019 (30), 3432–3455. https://doi.org/10.1002/ejic.201900375.
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Venter, P.; Causon, T.; Pasch, H.; de Villiers, Andre. Comprehensive Analysis of Chestnut Tannins by Reversed Phase and Hydrophilic Interaction Chromatography Coupled to Ion Mobility and High Resolution Mass Spectrometry. Anal. Chim. Acta 2019, 1088 (Copyright (C) 2021 American Chemical Society (ACS). All Rights Reserved.), 150–167. https://doi.org/10.1016/j.aca.2019.08.037.
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Venter, P.; Pasch, H.; de Villiers, Andre. Comprehensive Analysis of Tara Tannins by Reversed-Phase and Hydrophilic Interaction Chromatography Coupled to Ion Mobility and High-Resolution Mass Spectrometry. Anal. Bioanal. Chem. 2019, 411 (24), 6329–6341. https://doi.org/10.1007/s00216-019-01931-x.
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Venter, J.; Perez, C.; van Otterlo, W. A. L.; Martinez, A.; Blackie, M. A. L. 1-Aryl-3-(4-Methoxybenzyl)Ureas as Potentially Irreversible Glycogen Synthase Kinase 3 Inhibitors: Synthesis and Biological Evaluation. Bioorg. Med. Chem. Lett. 2019, 29 (13), 1597–1600. https://doi.org/10.1016/j.bmcl.2019.04.049.
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Viktor, Z.; Farcet, C.; Moire, C.; Brothier, F.; Pfukwa, H.; Pasch, Harald. Comprehensive Two-Dimensional Liquid Chromatography for the Characterization of Acrylate-Modified Hyaluronic Acid. Anal. Bioanal. Chem. 2019, 411 (15), 3321–3330. https://doi.org/10.1007/s00216-019-01799-x.